# PantheonOS **Repository Path**: anonyteam/PantheonOS ## Basic Information - **Project Name**: PantheonOS - **Description**: No description available - **Primary Language**: Unknown - **License**: BSD-2-Clause - **Default Branch**: main - **Homepage**: None - **GVP Project**: No ## Statistics - **Stars**: 0 - **Forks**: 0 - **Created**: 2026-05-01 - **Last Updated**: 2026-05-01 ## Categories & Tags **Categories**: Uncategorized **Tags**: None ## README
PantheonOS — A framework for building evolvable and distributed multi-agent systems. [Official Site][official-site] · [Online App][online-app] · [Desktop App][desktop-release-link] · [Documents][docs] · [Feedback][github-issues-link] [official-site]: https://pantheonos.stanford.edu/ [online-app]: https://app.pantheonos.stanford.edu/ [docs]: https://pantheonos.readthedocs.io/en/latest/
[![][website-shield]][website-link] [![][online-app-shield]][online-app] [![][desktop-shield]][desktop-release-link] [![][store-shield]][store-link] [![][manuscript-shield]][manuscript-link] [![][slack-shield]][slack-link] [![][discord-shield]][discord-link] [![][x-shield]][x-link]
[![][github-contributors-shield]][github-contributors-link] [![][github-forks-shield]][github-forks-link] [![][github-stars-shield]][github-stars-link] [![][github-issues-shield]][github-issues-link] [![][github-license-shield]][github-license-link] [![][pypi-shield]][pypi-link] [![][python-shield]][python-link] [![][status-shield]]()
## `1` [What is PantheonOS?](#1-what-is-pantheonos) PantheonOS is an **evolvable and privacy-preserving multi-agent framework** designed to reconcile generality with domain specificity. PantheonOS automates, scales and accelerates data sciences, with a particular focus on end-to-end single cell biology analyses. Cruicially, PantheonOS leverages agentic code evolution to optimize state-of-the-art and nascent algorithms, achieving super-human performance on specialized scientific tasks. ### Key Highlights - **Evolvable** — Pantheon-Evolve module enables agents to improve algorithms and code through genetic-algorithm-driven agentic code evolution - **Multi-Agent Teams** — PantheonTeam, Sequential, Swarm, Mixture-of-Agents (MoA), and AgentAsTool team patterns for flexible orchestration - **Distributed Architecture** — NATS-based messaging for scalable, fault-tolerant deployments across machines - **Friendly Interfaces** — Interactive CLI (`pantheon cli`) and Chatroom UI (`pantheon ui`) - **[Pantheon Store](https://app.pantheonos.stanford.edu/#/store)** — A community marketplace with 1,000+ curated agents, teams, and skills for biomedical AI, installable via UI or CLI ## `2` [Quick Start & Community](#2-quick-start--community) | | | | :--- | :--- | | [![][online-app-shield]][online-app] | Play with our Web UI! | | [![][desktop-shield]][desktop-release-link] | Download the latest desktop app release. | | [![][store-shield]][store-link] | Browse 1,000+ agents, teams, and skills! | | [![][pypi-shield]][pypi-link] | `pip install pantheon-agents` | | [![][slack-shield-badge]][slack-link] | Join our Slack community! | | [![][discord-shield-badge]][discord-link] | Join our Discord community! | ## `3` [Installation](#3-installation) ### Desktop App Download the latest Pantheon Desktop app: - [Desktop release page][desktop-release-link] Open the release page to download the latest version for your platform. ### Using uv (Recommended) [uv](https://github.com/astral-sh/uv) is a fast Python package manager that handles dependencies efficiently. ```bash # Install uv (if not already installed) # macOS/Linux curl -LsSf https://astral.sh/uv/install.sh | sh # Windows powershell -c "irm https://astral.sh/uv/install.ps1 | iex" # Clone and install git clone https://github.com/aristoteleo/PantheonOS.git cd PantheonOS uv sync # With optional dependencies uv sync --extra knowledge # RAG/vector search support uv sync --extra claw # PantheonClaw mobile gateway channels uv sync --extra r # R language support (requires R installed) ``` ### Using pip ```bash # Basic installation pip install pantheon-agents # With optional dependencies pip install "pantheon-agents[knowledge]" # RAG/vector search support pip install "pantheon-agents[claw]" # PantheonClaw mobile gateway channels ``` ### Development Installation ```bash git clone https://github.com/aristoteleo/PantheonOS.git cd PantheonOS uv sync --extra dev --extra knowledge # Run tests uv run pytest tests/ ``` ### Using Docker [![Docker Pulls](https://img.shields.io/docker/pulls/nanguage/pantheon-agents)](https://hub.docker.com/r/nanguage/pantheon-agents) Run Pantheon in a containerized environment with everything pre-configured: ```bash # Pull the image docker pull nanguage/pantheon-agents:latest # Run in standalone mode (for local use) docker run -it --rm \ -e PANTHEON_MODE=standalone \ -v $(pwd)/workspace:/workspace \ -p 8080:8080 \ nanguage/pantheon-agents:latest ``` After startup, copy the displayed connection URL to your browser and start using Pantheon! For detailed Docker usage, deployment modes, and configuration options, see the [Docker documentation](https://github.com/aristoteleo/PantheonOS/tree/main/pantheon-agents/docker). ## `4` [Usage](#4-usage) ### CLI Mode ```bash # Start the interactive REPL pantheon cli ``` ### Chatroom UI ```bash # Start the multi-agent chatroom pantheon ui --auto-start-nats --auto-ui ``` ### API Usage Please refer to our [Documents][docs] for detailed API usage, including creating agents, using toolsets, and building teams. ## `5` [Contributing](#5-contributing) Contributions of all types are more than welcome! Whether it's publishing skills to the [Pantheon Store][store-link] or contributing code, feel free to check out our GitHub [Issues][github-issues-link] to dive in. [![][pr-welcome-shield]][pr-welcome-link] [![][store-contribute-shield]][store-link] ## License This project is [BSD 2-Clause](./LICENSE) licensed. Copyright © 2026 [Qiu Lab](https://www.devo-evo.com/). 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